Simulation and Modeling

70s

90s

80s

Molecular models

Pharmacokinetics

Dedicated programs

Scientific problems

Specialists

Process kinetics

Population PK/PD

Production schedules

Simple work processes

Dedicated programs

Stat/math packages

PC based

Wider use

Systems models

Sim. Clin. trials

GUI tools

Non-specialist

Commun. value

GI Model

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