Simulation and Modeling at Eli Lilly

12/10/2000


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Table of Contents

Simulation and Modeling at Eli Lilly

Why do we model? (these are probably in order)

Simulation and Modeling

Simulation Issues

Black Box Syndrome

Black Box Revealed

Chemical Process Modeling early-mid 1980's

Simulation and Modeling

Chemical Process

Production Tank

Insert data slides from model

Simulation and Modeling

GI Model

GI Model

Lilly Modelling Conference 5/87

Simulation and Modeling

Process Phase II Costs/Mercer/Distr

Pig in a snake

Model Criticism

100Years/2500/SSinit

Simulation and Modeling

Lilly Development Strategy

Project Flow Models

Project Flow Model

Goal and Objective

Models Developed

Simplified 400 Day Process Focuses on critical path(s)

It really is a pipe... (apologies to Magritte)

But it leaks....

Some spots leak more than others.....

The flow time between holes is variable....

The model describes how big the holes are and the time between them....

We can insert probes...

We observe the cumulative effects of holes and flows and the parameters that influence those. Since we control these, we can test scenarios....

Milestones & Critical Path

Example: Fate of Projects

Insert Slides fromModel

We need to know?

Simulation and Modeling

Speke Automation Strategy

Decision Sciences Two- Tiered Approach

Project Outcomes

Decision Quality Wheel

Customer Satisfaction

Speke Automation Strategy problem

Speke Automation Strategy process

Speke Automation Strategy

Speke Automation Strategy score

Simulation and Modeling

PPT Slide

Tools: A monte carlo simulation model of the problem was developed for in depth analysis of the following information:

Outcome

Score

Simulation and Modeling

Insert BioDev Rethink slides

Simulation and Modeling

Milestones & Critical Path

Example Fate of Projects

Web Server

Current Applications

"There are many ways to summarize the limitations of the representation paradigm, the idea that knowledge consists basically in making maps of the world. But the simplest way to state the problem with maps is: they leave out the mapmaker... And no matter how different the various postmodern attacks were, they were all united in an attack on the representation paradigm."

"The model is of necessity flawed. Were this not so, it would be the thing itself."

Author: J. Richard Delbauve, Alph Bingham